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Item number: Cay30878-1

Bimosiamose is a pan-selectin inhibitor (IC50s = 88, 20, and 86 µM for E-, P-, and L-selectin, respectively). It reduces adhesion of HL-60 cells to E- and P-selectin when used at a concentration of 129 µM. In vivo, bimosiamose (200 mg/kg) reduces skin scaliness, induration, and erythema in a patient-derived...

Keywords:	TBC 1269, 3',3'''-(1,6-hexanediyl)bis[6'-(alpha-D-mannopyranosyloxy)-[1,1'-biphenyl]-3-acetic acid
Application:	pan Selectin inhibitor
CAS	187269-40-5
MW:	862.9 D

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