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Item number: Cay18889-5

NS 309 is a nonselective activator of small- and intermediate-conductance Ca2+-activated K+ (SK/KCa2 and IK/KCa3.1) channels (EC50s range from 0.12-1.2 µM for SK channels and 10-90 nM for IK channels). It can also activate voltage-gated Kv11.1 channels (hERG, IC50 = 1 µM), but does not, however, affect large...

Keywords:	6,7-dichloro-1H-indole-2,3-dione 3-oxime
Application:	SK/KCa2 & IK/KCa3.1 channel activator
CAS	18711-16-5
MW:	231 D

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