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AMD 3465 hexahydrobromide
AMD 3465 hexahydrobromide

Item number: TGM-T7208-100mg

Description: AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) is a CXCR4 receptor antagonist with potential anticancer and anti-HIV activity. Target: HIV Protease, CXCR. Smiles: Br.Br.Br.Br.Br.Br.C(NCc1ccccn1)c1ccc(CN2CCCNCCNCCC NCC2)cc1. References: Hatse S, et al. AMD3465, a monomacrocyclic CXCR4...
Keywords: GENZ-644494 (hexahydrobromide)
Application: CXCL12 inhibitor, CXCR4 antagonist
CAS 185991-07-5
MW: 896.07 D
From 34.00€ *
Review
AMD 3465 (hydrobromide)
AMD 3465 (hydrobromide)

Item number: Cay11959-5

C-X-C chemokine receptor type 4 is a receptor for the stromal cell-derived factor-1 which is designated as chemokine ligand 12 (CXCL12). It is involved in cell progression, hematopoiesis, cancer, HIV entry, and rheumatoid arthritis. AMD 3465 blocks the cell surface binding of CXCL12 with an IC50 value of 18 nM. It...
Keywords: N-[[4-(1,4,8,11-tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-2-pyridinemethanamine, hexahydrobromide
Application: CXCL12 inhibitor, CXCR4 antagonist
CAS 185991-07-5
MW: 896.1 D
From 129.00€ *
Review