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Item number: TGM-T15301-100mg

Description: Fluspirilene (R 6218) is a non-competitive L-type calcium channel antagonist (IC50: 0.03 µM).Fluspirilene is a long-acting antipsychotic compound used in the treatment of schizophrenia. Target: Calcium Channel. Smiles: Fc1ccc(cc1)C(CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccc(F)cc1. References: Kenny BA, et...

Keywords:	R 6218, Redeptin
Application:	Antipsychotic
CAS	1841-19-6
MW:	475.57 D

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Fluspirilene

Item number: Cay19530-5

Fluspirilene is a dopamine D2 and D3 receptor antagonist (Kis = 1.5 and 1.1 nM, respectively). It is selective for dopamine D2 and D3 receptors over dopamine D1, alpha1- and alpha2-adrenergic, H1 histamine, and sigma-1 (sigma1) receptors (Kis = 450, 102, >5,000, 540, and 150 nM, respectively), muscarinic...

Keywords:	McN-JR 6218, R 6218, Redeptin, 8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Application:	Calcium channel blocker, dopamine receptor antagonist
CAS	1841-19-6
MW:	475.6 D

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