Description: N-Lactoyl-Phenylalanine (Lac-Phe) is a peptide coupling of lactic acid and phenylalanine, one of the metabolites in acute exercise, which can be used in the study of obesity and metabolism-related diseases. Target: Endogenous Metabolite. Smiles: C([C@H](NC([C@H](C)O)=O)C(O)=O)C1=CC=CC=C1. References: Li...

Lactoyl phenylalanine is a secondary metabolite. It is formed from lactate and phenylalanine by cytosolic non-specific dipeptidase (CNDP2). Lactoyl phenylalanine (50 mg/kg per day) decreases food intake, body weight, and adiposity, as well as improves glucose homeostasis in a mouse model of high-fat diet-induced...

Appearance: White to off-white powder. Solubility: Soluble in water. InChi Key: TXEKHKMVDUMVBF-GNAZCLTHSA-M Smiles: C[C@H](O)C(N[C@@H](CC1=CC=CC=C1)C(O)=O)=O.CC([O-2])=O Lac-Phe is an exercise-inducible metabolite, also called exerkine, that suppresses feeding and obesity. Lac-Phe is increased heavily with exercise...