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Item number: SYN-3046-M001

AZ9482 is a potent and selective PARP inhibitor featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. AZ9482 exhibits very potent centrosome declustering activity in HeLa cells (EC50 < 18nM). AZ9482 also showed a 3nM GI50 in the DLBCL cell line OCI-LY-19 in a 3-day AlamarBlue assay. Consistent with...

Keywords:	2-(4-(3-((4-Oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)nicotinonitrile
Application:	Potent, selective PARP inhibitor
CAS	1825345-33-2
MW:	450.5 D

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AZ9482

Item number: TGM-T22264-100mg

Description: AZ9482 is a selective and potent inhibitor of PARP featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. AZ9482 exhibits very potent activity of centrosome declustering with EC50 of < 18 nM in HeLa cells. Target: PARP. Smiles: O=C(N1CCN(CC1)c1ncccc1C#N)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1....

Application:	PARP inhibitor
CAS	1825345-33-2
MW:	450.49 D

From 52.00€ *

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