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KG-501
KG-501

Item number: TGM-T7297-100mg

Description: KG-501 (Naphthol AS-E phosphate) is a cAMP response element-binding protein (CREB) inhibitor(IC50 : 6.89 µM). Target: Epigenetic Reader Domain. Smiles: C(NC1=CC=C(Cl)C=C1)(=O)C=2C(OP(=O)(O)O)=CC3=C(C2)C=CC=C3. References: Kaori K , Haruka F , Hitomi S , et al. The Traditional Japanese Herbal Medicine...
Keywords: Naphthol AS-E phosphate
Application: CREB - CREBBP-KIX domain interaction inhibitor
CAS 18228-17-6
MW: 377.72 D
From 31.00€ *
Review
Naphthol AS-E phosphate
Naphthol AS-E phosphate

Item number: CDX-N0125-G001

Beige powder. Histochemical substrate for alkaline phosphatases. Aldolase inhibitor. Small molecule inhibitor. Anticancer compound that directly targets the KIX domain of CBP, resulting in a disrupted CREB-CBP complex, inhibited CREB-target gene induction and inhibited IL-1beta-mediated angiogenic activity in...
Keywords: N-(4-Chlorophenyl)-3-(phosphonooxy)naphthalene-2-carboxamide, KG-501, NASEP
Application: Histochemical alkaline phosphatase substrate, CREB-CBP complex disruptor
CAS 18228-17-6
MW: 377,72 D
From 138.00€ *
Review
Naphthol AS-E Phosphate
Naphthol AS-E Phosphate

Item number: Cay33602-10

Naphthol AS-E phosphate is an inhibitor of the protein-protein interaction between CREB and the KIX domain of CREB-binding protein (CBP, Ki = 50 µM). It also inhibits the binding of the transcription factor Myb to the KIX domains of p300 and CBP (IC50s = 30 and 43 µM, respectively). Naphthol AS-E phosphate inhibits...
Keywords: KG-501, N-(4-chlorophenyl)-3-(phosphonooxy)-2-naphthalenecarboxamide
Application: CREB - CREBBP-KIX domain interaction inhibitor
CAS 18228-17-6
MW: 377.7 D
From 86.00€ *
Review