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BMS 195614

Item number: Cay16029-1

BMS 195614 is a neutral retinoic acid receptor (RAR) alpha-selective antagonist (Ki = 2.5 nM). It antagonizes agonist-induced coactivator recruitment and moderately decreases SMRT binding to RAR but does not significantly affect nuclear receptor corepressor binding.Formal Name:...

Keywords:	BMS 614, 4-[[[5,6-dihydro-5,5-dimethyl-8-(3-quinolinyl)-2-naphthalenyl]carbonyl]amino]-benzoic acid
Application:	RARA antagonist
CAS	182135-66-6
MW:	448.5 D

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