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Item number: TGM-T16891-1mL

Description: SKA-121 is a selective KCa3.1 activator (EC50s: 109 nM and 4.4 µM for KCa3.1 and KCa2.3, respectively). Target: Others. Smiles: Cc1cc2nc(N)oc2c2ccccc12. References: Coleman N, et al. New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1.Mol Pharmacol. 2014 Sep,86(3):342-57.

Application:	KCNN4 / IKCa1 / KCa3.1 modulator
CAS	1820708-73-3
MW:	198.22 D

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SKA-121

Item number: Cay9003088-1

SKA-121 is a positive-gating modulator of intermediate-conductance calcium-activated potassium channels (IKCa1/KCa3.1) with an EC50 value of 109 nM using whole-cell patch-clamp electrophysiology with calcium in the internal solution. It is selective for KCa3.1 over KCa2.1, KCa2.2 and KCa2.3 (EC50s = 8,700, 6,800,...

Keywords:	5-methyl-naphth[2,1-d]oxazol-2-amine
Application:	KCNN4 / IKCa1 / KCa3.1 modulator
CAS	1820708-73-3
MW:	198.2 D

From 37.00€ *

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