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Item number: TGM-T21687-10mg

Description: Conoidin A is a cell-permeable inhibitor of the T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. It covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation activity with an IC50 of 23 µM. It also inhibits hyperoxidation of mammalian...

CAS	18080-67-6
MW:	347.99 D

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Conoidin A

Item number: Cay15605-25

Peroxiredoxins are a widely conserved family of enzymes that function in antioxidant defense and act in redox signaling pathways. Increased expression of human peroxiredoxin is associated with cancer, cardiovascular dysfunction, and neurodegeneration. Conoidin A inactivates peroxiredoxins by covalently binding to...

Keywords:	2,3-bis(bromomethyl)-quinoxaline 1,4-dioxide
Application:	Peroxiredoxin inhibitor
CAS	18080-67-6
MW:	348 D

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