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LG100754
LG100754

Item number: TGM-T15748-100mg

Description: LG100754 (UVI 2112) is an insulin sensitizer that functions through RXR. LG100754 is an RXR dimer modulator. LG100754 acts as an RXR: RXR homodimer antagonist, but functions as an agonist towards RXR: PPARalpha and RXR: PPARgamma heterodimers. Target: PPAR. Smiles:...
Keywords: UVI 2112
Application: RXR homodimer antagonist, RXR:PPAR alpha/gamma heterodimer agonist
CAS 180713-37-5
MW: 396.56 D
From 973.00€ *
Review
LG 100754
LG 100754

Item number: Cay19647-1

LG 100754 is a ligand of retinoid X receptor (RXR) that modulates the activity of RXR dimers. It acts as an antagonist towards RXR homodimers but as an agonist of heterodimers consisting of RXR and retinoic acid receptor (RAR) or PPARs. LG 100754, at 1 µM, is a weak agonist of RXR-PPARgamma but strongly enhances...
Keywords: CD3159, LGD 100754, UVI2112,...
Application: RXR homodimer antagonist, RXR:PPAR alpha/gamma heterodimer agonist
CAS 180713-37-5
MW: 396.6 D
From 43.00€ *
Review