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IRAK4-IN-7
IRAK4-IN-7

Item number: TGM-T5354-100mg

Description: IRAK4-IN-7 (CA-4948) is a selective and potent IRAK4 kinase inhibitor with in vivo activity in a TLR4-induced cytokine release model. Target: IRAK. Smiles: Nc1ccc(cn1)-c1cccc(n1)C(=O)Nc1cnc2nc(oc2c1)N1CCOCC1. References: Robert N. Booher, et al. Abstract 1168: Efficacy of the IRAK4 inhibitor CA-4948 in...
Keywords: CA-4948
Application: IRAK-4 inhibitor
CAS 1801343-74-7
MW: 417.42 D
From 34.00€ *
Review
CA-4948
CA-4948

Item number: Cay27598-1

CA-4948 is an orally bioavailable inhibitor of interleukin-1 receptor associated kinase-4 (IRAK-4). It has antitumor activity in ABC-type diffuse large B cell lymphoma patient-derived xenograft (PDX) mouse models.Formal Name: 6'-amino-N-[2-(4-morpholinyl)oxazolo[4,5-b]pyridin-6-yl]-[2,3'-bipyridine]-6-carboxamide....
Keywords: 6'-amino-N-[2-(4-morpholinyl)oxazolo[4,5-b]pyridin-6-yl]-[2,3'-bipyridine]-6-carboxamide
Application: IRAK-4 inhibitor
CAS 1801343-74-7
MW: 417.4 D
From 44.00€ *
Review