3 products were found matching "1800398-38-2"!

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Item number: LKT-L930280.1

LXH254 is a type II RAF inhibitor. SMILES: CC1=C(C=C(C=C1)NC(=O)C2=CC(=NC=C2)C(F)(F)F)C3=CC(=NC(=C3)OCCO)N4CCOCC4

Keywords:	Naporafenib,...
Application:	pan-RAF inhibitor
CAS	1800398-38-2
MW:	502.49 D

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LXH254

Item number: TGM-T11898-100mg

Description: LXH254 is a potent C-Raf and B-Raf inhibitor. Target: Raf. Smiles: Cc1ccc(NC(=O)c2ccnc(c2)C(F)(F)F)cc1-c1cc(OCCO)nc(c1)N1CCOCC1. References: CAPONIGRO, Giordano, et al. THERAPEUTIC COMBINATIO NSCOMPRISI NGARAFINHI BITORANDAE RKINHIBITO R. WO 2018051306 A1 20180322

Application:	Targets B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1] (BRAF)
CAS	1800398-38-2
MW:	502.49 D

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LXH254

Item number: Cay28231-1

LXH254 is a pan-RAF inhibitor that selectively inhibits B-RAF and C-RAF over a panel of 456 human kinases. It inhibits MAPK signaling in tumor cells expressing mutant B-RAFV600. LXH254 induces tumor regression in various mouse xenograft models.Formal Name:...

Keywords:	N-[3-[2-(2-hydroxyethoxy)-6-(4-morpholinyl)-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)-4-pyridinecarboxamide
Application:	pan-RAF inhibitor
CAS	1800398-38-2
MW:	502.5 D

From 85.00€ *

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