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Item number: Cay23766-2.5

Tetromycin B is a cysteine protease inhibitor with Ki values of 0.62, 1.42, 32.5, and 1.59 µM for rhodesain, falcipain-2, cathepsin L, and cathepsin B, respectively. It inhibits the growth of T. brucei in vitro (IC50 = 30.87 µM). Tetromycin B is also cytotoxic to HEK293T kidney cells and J774.1 macrophages (IC50s =...

Keywords:	(1S,4S,4aS,6aR,7E,11E,12aR,15R,16aS,20aS,20bR)-2,3,4,4a,6a,9,10,12a,15,16,20a,20b-dodecahydro-4,21-trihydroxy-1,6,7,11,12a...
Application:	Cysteine protease inhibitor
CAS	180027-84-3
MW:	534.7 D

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