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Item number: Cay33387-1

Borussertib is a covalent and allosteric Akt1 and Akt2 inhibitor (Kis = 2 and 6 nM, respectively). It is selective for Akt1 and Akt2 over Akt3 (Ki = 91 nM). Borussertib (5 µM) reduces viability in Ba/F3 cells expressing human Akt1 or Akt2 but not Ba/F3 cells expressing human Akt3. It decreases the levels of...

Keywords:	N-[3-[1-[[4-(5,6-dihydro-5-oxo-3-phenyl-1,6-naphthyridin-2-yl)phenyl]methyl]-4-piperidinyl]-2,3-dihydro-2-oxo-1H-benzimida...
Application:	Akt1 / Akt2 inhibitor
CAS	1800070-77-2
MW:	596.7 D

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