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Item number: Cay24684-1

Centrinone is an inhibitor of polo-like kinase 4 (Plk4, Ki = 0.16 nM). It is greater than 1,100- and 2,800-fold selective for Plk4 over Aurora A and Aurora B kinases, respectively, and a panel of 442 kinases at 100 nM. Centrinone (125 nM) depletes centrosomes and induces apoptosis in HeLa cells.Formal Name:...

Keywords:	LCR-263,...
Application:	Plk4 inhibitor
CAS	1798871-30-3
MW:	633.6 D

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