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Item number: TGM-T4383-100mg

Description: GSK-J4 Hydrochloride (GSK J4 HCl) is a cell permeable, potent and selective histone demethylase(JMJD3 )inhibitor. is an ethyl ester derivative of the GSK-J1 with an IC50 value greater than 50 µM in vitro. Target: Histone Demethylase. Smiles: Cl.CCOC(=O)CCNc1cc(nc(n1)-c1ccccn1)N1CCc2ccccc2CC1....

Keywords:	GSK J4 HCl, GSK J4 HCl (1373423-53-0 free base)
Application:	Histone demethylase inhibitor
CAS	1797983-09-5
MW:	453.97 D

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GSK-J4 (hydrochloride)

Item number: Cay12073-5

The histone H3 lysine 27 (H3K27) demethylase JMJD3 plays important roles in the transcriptional regulation of cell differentiation, development, the inflammatory response, and cancer. GSK-J4 (hydrochloride) is an ethyl ester derivative of the JMJD3 selective histone demethylase inhibitor GSK-J1 (Cay-12054) with an...

Keywords:	N-[2-(2-pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-beta-alanine, ethyl ester, monohydrochloride
Application:	Histone demethylase inhibitor
CAS	1797983-09-5
MW:	454 D

From 77.00€ *

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