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GSK-J1 sodium salt
Item number: TGM-T71916-10mg
Description: GSK-J1 sodium salt is a potent inhibitor of the H3K27 histone demethylases JMJD3 and UTX. Target: Others. Smiles: [Na+].[O-]C(=O)CCNc1cc(nc(n1)-c1ccccn1)N1CCc2ccccc2CC1
| Application: | JMJD3 inhibitor |
| CAS | 1797832-71-3 |
| MW: | 411.4408 D |
From 77.00€
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GSK-J1 (sodium salt)
Item number: Cay12054-5
The histone H3 lysine 27 (H3K27) demethylase JMJD3 plays important roles in the transcriptional regulation of cell differentiation, development, the inflammatory response, and cancer. GSK-J1 is a potent inhibitor of the H3K27 histone demethylases JMJD3 and UTX (IC50s = 18 and 56 µM, respectively as measured by mass...
| Keywords: | N-[2-(2-pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-beta-alanine, monosodium salt |
| Application: | JMJD3 inhibitor |
| CAS | 1797832-71-3 |
| MW: | 411.4 D |
From 43.00€
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