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MZ 1
Item number: TGM-T5436-100mg
Description: MZ 1 is a BRD4 protein degrader based on PROTAC technology. Target: Epigenetic Reader Domain, PROTACs. Smiles: CC=1C2=C(N3C([C@H](CC(NCCOCCOCCO CC(N[C@H](C(=O)N4[C@H](C(NCC5=CC=C(C=C5)C6=C(C)N=CS6)=O)C[C@@H](O)C4)C(C)(C)C)=O)=O)N=C2C7=CC=C(Cl)C=C7)=NN=C3C)SC1C. References: Gadd MS, et al. Structural...
| Application: | Protac(R) reagent |
| CAS | 1797406-69-9 |
| MW: | 1002.64 D |
From 46.00€
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MZ1
Item number: Cay21622-1
MZ1 is a hybrid compound that drives the selective proteasomal degradation of bromodomain-containing protein 4 (BRD4). It is characterized as a proteolysis-targeting chimera (PROTAC) and contains JQ-1, which binds bromo- and extra-terminal (BET) proteins, linked to a ligand for the E3 ubiquitin ligase VHL. MZ1...
| Keywords: | (4R)-N-[14-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]-1,13-dioxo-3... |
| Application: | BRD4 degradation promotor |
| CAS | 1797406-69-9 |
| MW: | 1002.6 D |
From 66.00€
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MZ1
Item number: BPS-82056
MZ1 is a PROTAC compound that is selective for proteasomal degradation of bromodomain-containing protein 4 (BRD4) in HeLa cells . MZ1 contains JQ-1, which binds bromo- and extra-terminal (BET) proteins, linked to a ligand for the E3 ubiquitin ligase VHL.
| Application: | Protac(R) reagent |
| CAS | 1797406-69-9 |
| MW: | 1002,7 D |
1,760.00€
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