Description: Caspofungin Acetate (MK 0991) is the acetate salt of an antimycotic echinocandin lipopeptide, semisynthetically derived from a fermentation product of the fungus Glarea lozoyensis. This agent is active against Aspergillus and Candida species. Target: Antibiotic, Antifungal. Smiles:...

Caspofungin is an echinocandin antifungal originally isolated from G. lozoyensis and a derivative of pneumocandin B0 (Cay-21527). It is active against 3,959 Candida clinical isolates (MIC90 = 1 µg/ml), including isolates resistant to fluconazole (Cay-11594) or itraconazole (Cay-13288), as well as 38 Aspergillus...

Caspofungin acetate is a lipopeptide antifungal that inhibits the enzyme 1,3-beta-Glucan synthase, which synthesizes -glucan polymers that form fungal cell walls. Caspofungin acetate is active against a variety of Aspergillus and Candida species and unlike many antifungals, is not metabolized by the cytochrome p450...

White to beige powder Soluble in DMSO (25mg/ml), DMF (20mg/ml), ehtanol (20mg/ml) or water (15mg/ml). Chemical. CAS: 179463-17-3. Formula: C52H88N10O15 · 2C2H4O2. MW: 1213.42. Caspofungin acetate is an antifungal compound that is classified as an echinocandin. It is a semi-synthetic analogue of pneumocandin B0 with...