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![Z-Leu-Leu-Leu-B(OH)2 [MG-262]](https://www.biomol.com/media/image/c1/3d/5e/AG-CP3-0024-M001_200x200.png "Z-Leu-Leu-Leu-B(OH)2 [MG-262]")
Z-Leu-Leu-Leu-B(OH)2 [MG-262]
Item number: AG-CP3-0024-C200
Solid lyophilized powder. Soluble in DMSO. Highly potent and selective cell permeable inhibitor of the proteasome. Inhibits the chymotrypsin-like and caspase-like peptidase activity of the proteasome, Calpain and cathepsin inhibitor, Autophagy activator, Similar structure as MG-132 (AG-CP3-0011) but much higher...
| Keywords: | Z-LLL-B(OH)2, Proteasome Inhibitor III |
| Application: | Proteasome inhibitor |
| CAS | 179324-22-2 |
| MW: | 491,4 D |
From 77.00€
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Z-Leu-Leu-Leu-B(OH)2
Item number: Cay10008311-1
Z-Leu-Leu-Leu-B(OH)2 is a proteasome inhibitor with diverse biological activities. It inhibits LPS-induced expression of FMS-related tyrosine kinase 1 (FLT1) in isolated human microvascular endothelial cells and macrophages. Z-Leu-Leu-Leu-B(OH)2 (1 µM) reduces heat shock-induced increases in heat shock protein 70...
| Keywords: | MG 262, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1R)-1-borono-3-methylbutyl]-L-leucinamide |
| Application: | Proteasome inhibitor |
| CAS | 179324-22-2 |
| MW: | 491.4 D |
From 401.00€
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