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Item number: TGM-T6801-100mg

Description: CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 µM). Target: Carboxypeptidase, DNA/RNA Synthesis. Smiles: Cn1c2ccccc2c(cc1=O)C(=O)Nc1ccc2OCCOc2c1. References: Sdelci S, et al. Nat Chem Biol. 2016, 12(7):504-10.

Application:	TAF1 bromodomain inhibitor
CAS	1790895-25-8
MW:	336.34 D

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CeMMEC13

Item number: Cay20224-1

CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 µM). It does not bind to bromodomains of BRD4, BRD9, or CREBBP. CeMMEC13 synergizes with (+)-JQ1 (Cay-11187) to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells.Formal Name:...

Keywords:	N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,2-dihydro-1-methyl-2-oxo-4-quinolinecarboxamide
Application:	TAF1 bromodomain inhibitor
CAS	1790895-25-8
MW:	336.3 D

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