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RP-001 hydrochloride
RP-001 hydrochloride

Item number: TGM-T12780L-10mg

Description: RP-001 hydrochloride is a selective agonist of picomolar short-acting S1P1 (EDG1)(EC50 of 9 pM), has little activity on S1P2-S1P4 and only moderate affinity for S1P5. Target: Others. Smiles: Cl.N#CC=1C=C(C=CC1OC(C)C)C2=NC(=NO2)C=3C=CC=C4C3CCC4NCCC(=O)O. References: Cahalan SM, et al. Actions of a...
Application: Potent S1P1 receptor agonist
CAS 1781880-34-9
MW: 468.93 D
From 93.00€ *
Review
RP 001 (hydrochloride)
RP 001 (hydrochloride)

Item number: Cay16636-1

RP 001 is a potent sphingosine-1-phosphate receptor 1 (S1P1) agonist (EC50 = 9 pM). It is competitive with W146 (Cay-10009109), a selective S1P1 antagonist, and induces internalization and polyubiquitination of S1P1 in a dose-dependent manner. RP 001 induces dose-dependent lymphopenia in mice (EC50 = 0.03 mg/kg). It...
Keywords: N-[4-[5-[3-cyano-4-(1-methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl]-beta-alanine, monohydrochloride
Application: Potent S1P1 receptor agonist
CAS 1781880-34-9
MW: 468.9 D
From 52.00€ *
Review