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RN-1 dihydrochloride
Item number: TGM-T21652-100mg
Description: RN-1 dihydrochloride is an effective and selective irreversible inhibitor of lysine-specific demethylase 1 (LSD1, IC50 = 70 nM). Target: Histone Demethylase, MAO. Smiles: Cl.Cl.CN1CCN(CC1)C(=O)CN[C@H]1C[C@@H]1c1ccc(OCc2ccccc2)cc1. References: Shuaiying Cui, et al. The LSD1 inhibitor RN-1 induces fetal...
| Application: | Irreversible LSD1 inhibitor |
| CAS | 1781835-13-9 |
| MW: | 452.42 D |
From 42.00€
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RN-1 (hydrochloride)
Item number: Cay18124-1
Lysine-specific demethylase 1 (LSD1) belongs to the family of flavin adenine dinucleotide (FAD)-dependent amine oxidases that include monoamine oxidases (MAOs). RN-1 is a potent, irreversible inhibitor of LSD1 (IC50 = 70 nM). It is much less effective against MAO-A and MAO-B (IC50s = 0.51 and 2.8 µM, respectively)....
| Keywords: | LSD1 Inhibitor IV, rel-1-(4-methyl-1-piperazinyl)-2-[[(1R,2S)-2-[4-(phenylmethoxy)phenyl]cyclopropyl]amino]-ethanone,... |
| Application: | Irreversible LSD1 inhibitor |
| CAS | 1781835-13-9 |
| MW: | 452.4 D |
From 78.00€
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