Description: CGP36216 hydrochloride acts as a selective antagonist at the presynaptic GABA receptor, specifically binding to the GABAB receptor with a Ki value of 0.3 µM. This compound is leveraged in research focused on anxiety and trauma-related disorders [1] [2]. Target: Others. Smiles: P(CCCN)(CC)(=O)O.Cl

CGP 36216 is a selective antagonist of GABAB receptors (IC50 = 43 µM). Its action is reversed by the GABAB receptor agonist baclofen. It is active at presynaptic, but not postsynaptic, receptors.Formal Name: p-(3-aminopropyl)-p-ethyl-phosphinic acid, monohydrochloride. CAS Number: 1781834-71-6. Molecular Formula:...