2 products were found matching "1780372-25-9"!
No results were found for the filter!
SB 243213 dihydrochloride
Item number: TGM-T12859L-1mg
Description: SB 243213 dihydrochloride is an orally active, selective, and high-affinity antagonist of the 5-hydroxytryptamine (5-HT)2C receptor, with a pKi of 9.37 and a pKb of 9.8 for the human 5-HT2C receptor. Target: 5-HT Receptor. Smiles: O=C(N1C2=C(CC1)C=C(C)C(C(F)(F)F)=C2)NC3=CN=C(C=C3)OC4=CC=CN=C4C.Cl.Cl....
| Application: | 5-HT2C receptor inverse agonist |
| CAS | 1780372-25-9 |
| MW: | 501.33 D |
From 108.00€
*
SB-243213 (hydrochloride)
Item number: Cay36217-1
SB-243213 is an inverse agonist of the serotonin (5-HT) receptor subtype 5-HT2C. It is selective for 5-HT2C over 5-HT2A and 5-HT2B receptors (Kis = 0.001, 0.158, and 0.1 µM, respectively) and the cytochrome P450 (CYP) isoforms CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4 (IC50s = >100, 23, >100, >100, and >100 µM,...
| Keywords: | 2,3-dihydro-5-methyl-N-[6-[(2-methyl-3-pyridinyl)oxy]-3-pyridinyl]-6-(trifluoromethyl)-1H-indole-1-carboxamide,... |
| Application: | 5-HT2C receptor inverse agonist |
| CAS | 1780372-25-9 |
| MW: | 501.3 D |
From 60.00€
*
