Description: ZINC03129319 is an inhibitor of dengue virus (DENV) NS2B-NS3 protease. Target: Virus Protease. Smiles: O=C1C2(N3[C@](CS2)(C(=O)N4[C@@](C3=O)(CSC45C(=O)C=6C(C5=O)=CC=CC6)[H])[H])C(=O)C=7C1=CC=CC7. References: Watowich, Stanley J, et al. SMALL-MOLECULE INHIBITORS OFDENGUE VIRUS PROTEASES. US20150141521A1.

DSDP is an activator of stimulator of interferon genes (STING). It induces expression of an IFN-stimulated gene 54 (ISG54) luciferase reporter in HepAD38 cells that constitutively express human cyclic GMP-AMP synthase (cGAS) and STING. DSDP (50 µM) increases IFNB1, TNFA, and IL29 expression in HepG2 cells expressing...