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Item number: TGM-T16816-10mg

Description: S 18986 is a selective, orally active, brain-penetrant positive allosteric modulator of AMPA-type receptors that enhances cognition in rodents by inducing the release of noradrenaline and acetylcholine in the rat hippocampus, subsequently improving object-recognition memory. Target: GluR. Smiles:...

Application:	Glutamate ionotropic receptor positive allosteric modulator
CAS	175340-20-2
MW:	224.28 D

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S18986

Item number: Cay14937-1

S18986 is a positive allosteric modulator of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors that potently enhances (S)-AMPA-mediated noradrenaline release in rat hippocampal and frontal cortex slices. S18986 is orally bioavailable and penetrates the blood-brain barrier in animals....

Keywords:	2,3,3aS,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazine, 5,5-dioxide
Application:	Glutamate ionotropic receptor positive allosteric modulator
CAS	175340-20-2
MW:	224.3 D

From 44.00€ *

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