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CP 376395
Item number: TGM-T4329-100mg
Description: CP 376395 (CP-316311) is an effective and specific Corticotropin-releasing factor 1 (CRF1) receptor antagonist. Target: CRFR. Smiles: O(C1=C(C)C=C(C)C=C1C)C2=C(C)C(NC(CC)CC)=CC(C)=N2. References: Chen YL, et al. 2-aryloxy-4-alkylaminopyridines: discovery of novel corticotropin-releasing factor 1...
| Keywords: | CP-316311 |
| Application: | Corticotropin-releasing factor receptor 1 (CRFR-1) antagonist |
| CAS | 175140-00-8 |
| MW: | 326.48 D |
From 35.00€
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CP 376,395
Item number: Cay29188-1
CP 376,395 is an antagonist of corticotropin-releasing factor (CRF) receptor 1 (CRF1, IC50 = 5.1 nM). It inhibits adenylate cyclase activity stimulated by ovine CRF in rat cerebral cortex and at human CRF1 receptors. CP 376,395 (17.8 mg/kg) inhibits CRF-induced increases in the acoustic startle response in rats. It...
| Keywords: | CP 316311, N-(1-ethylpropyl)-3,6-dimethyl-2-(2,4,6-trimethylphenoxy)-4-pyridinamine |
| Application: | Corticotropin-releasing factor receptor 1 (CRFR-1) antagonist |
| CAS | 175140-00-8 |
| MW: | 326.5 D |
From 156.00€
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