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Item number: TGM-TQ0257-1mg

Description: FICZ (6-Formylindolo[3,2-b]carbazole) is a potent aryl agonist for the hydrocarbon receptor (AhR, Kd: 70 pM). Target: Aryl Hydrocarbon Receptor. Smiles: O=Cc1c2[nH]c3ccccc3c2cc2[nH]c3ccccc3c12. References: Mohammadi-Bardbori A, et al. The highly bioactive molecule and signal substance...

Keywords:	6-Formylindolo[3,2-b]carbazole
Application:	AhR agonist
CAS	172922-91-7
MW:	284.31 D

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6-Formylindolo[3,2-b]carbazole

Item number: Cay19529-1

6-Formylindolo[3,2-b]carbazole (FICZ) is a degradation product of tryptophan upon exposure to visible light that activates the aryl hydrocarbon receptor (AhR, Kd = 70 pM). This endogenous AhR ligand is also a good substrate for cytochromes P450 (CYP) 1A1, 1A2, and 1B1 (Kis = 15.4, 3.9, and 13.3 µM, respectively)....

Keywords:	FICZ, 5,11-dihydro-indolo[3,2-b]carbazole-6-carboxaldehyde
Application:	AhR agonist
CAS	172922-91-7
MW:	284.3 D

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