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PP1 (Src Inhibitor)
PP1 (Src Inhibitor)

Item number: Cay14244-1

PP1 is a potent, reversible, ATP-competitive, and selective inhibitor of the Src family of protein tyrosine kinases. It inhibits p56lck (IC50 = 5 nM), p59fynT (IC50 = 6 nM), Hck (IC50 = 20 nM), and Src (IC50 = 170 nM) without significantly affecting the activity of EGFR kinase (IC50 = 250 nM), JAK2 (IC50 = 50 µM),...
Keywords: AGL 1872, EI 275, 1-(1,1-dimethylethyl)-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Application: Tyrosine kinase inhibitor
CAS 172889-26-8
MW: 281.4 D
From 66.00€ *
Review
PP1
PP1

Item number: AG-CR1-3562-M005

Highly potent and selective Scr family tyrosine kinase inhibitor. Shows anti-Ras cancer potential by blocking Ras-induced activation of PAK1. Antitumor compound. RIP2 inhibitor. Blocks TGF-beta-mediated cellular responses.
Keywords: 4-Amino-5-(methylphenyl)-7-(tert.butyl)pyrazolo-(3,4-d)pyrimidine
Application: Tyrosine kinase inhibitor
CAS 172889-26-8
MW: 281,4 D
From 44.00€ *
Review
4-Amino-1-tert-butyl-3-(4-methylphenyl)pyrazolo[3,4-d]pyrimidine
4-Amino-1-tert-butyl-3-(4-methylphenyl)pyrazolo[3,4-d]pyr...

Item number: N0032-30.10

A highly potent and uniquely specific tyrosine kinase inhibitor of a rationally engineered v-Src tyrosine kinase. Melting Point: 190-192°C, Solubility: Chloroform, Ethyl Acetate, Method for Determining Identity: Proton NMR (CDCl3) Spectroscopic and Mass Spectrometric Analysis, TLC Conditions: SiO2:...
CAS 172889-26-8
MW: 281.3 kD
477.00€ *
Review
PP-1
PP-1

Item number: LKT-P6232.25

Src inhibitor.
Keywords: 4-Amino-1-tert-butyl-3-(4-methylphenyl)pyrazolo[3,4-d]pyrimidine
Application: Inhibitor of Src family tyrosine kinases
CAS 172889-26-8
MW: 281,36 D
From 198.00€ *
Review