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Item number: TGM-T2044-100mg

Description: Varespladib (LY315920), a specific and effective human non-pancreatic secretory phospholipase A2 (hnsPLA) inhibitor(IC50=7 nM), has been investigated for the treatment and prevention of sickle cell disease, vaso-occlusive crisis, and acute coronary syndrome. Target: Phospholipase. Smiles:...

Keywords:	LY315920
Application:	Targets platelet-activating factor acetylhydrolase [EC:3.1.1.47] (PLA2G7, PAFAH)
CAS	172732-68-2
MW:	380.39 D

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LY315920

Item number: Cay18267-5

LY315920 is an inhibitor of human group IIA (hGIIA) secretory phospholipase A2 (sPLA2, IC50 = 9 nM). It also potently inhibits human GIIE and GX isoforms, as well as the corresponding mouse isoforms, but poorly inhibits other PLA2 enzymes. LY315920 inhibits sPLA2-induced release of thromboxane A2 from isolated...

Keywords:	Varespladib, 2-[[3-(2-amino-2-oxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]-acetic acid
Application:	Secretory phospholipase A2 (PLA2) inhibitor
CAS	172732-68-2
MW:	380.4 D

From 117.00€ *

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