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Item number: Cay11983-1

Sonepiprazole is a selective antagonist of the dopamine 4 (D4) receptor (Kis = 10 nM). It is highly selective over D1, D2, and D3 receptors, serotonin 1A and 2 receptors, as well as alpha1- and alpha2-adrenergic receptors (Kis > 2,000 nM). Its safety profile in rat studies is improved in comparison to classical...

Keywords:	PNU 101387, U-101387, 4-[4-[2-[(1S)-3,4-dihydro-1H-2-benzopyran-1-yl]ethyl]-1-piperazinyl]-benzenesulfonamide
Application:	Dopamine D4 DRD4 antagonist
CAS	170858-33-0
MW:	401.5 D

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