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Aprepitant
Item number: Cay14867-10
Aprepitant an antiemetic and antagonist of the neurokinin-1 (NK1) receptor (Ki = 3 nM, IC50 = 0.09 nM for the human receptor). It is selective for NK1 over NK3 receptors (Ki = 454.1 nM for human NK3). In vivo, aprepitant (1 mg/kg) prevents plasma extravasation into the esophagus of guinea pigs induced by substance P...
| Keywords: | Emend, L-754,030, MK-869, ONO-7436,... |
| Application: | NK-1 receptor antagonist |
| CAS | 170729-80-3 |
| MW: | 534.4 D |
From 50.00€
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Aprepitant
Item number: LKT-A6368.10
NK1 antagonist.
| Keywords: | (2R)-[(1R)-3,5-bis(trifluoromethyl)phenylethoxy]-(3S)-(4-fluoro)phenyl-4-(3-oxo-1,2,4-triazol-5-yl)methyl morpholine,... |
| Application: | Tachykinin receptor 1 / neurokinin-1 receptor antagonist |
| CAS | 170729-80-3 |
| MW: | 534.43 D |
From 123.00€
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