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CD38 inhibitor 1
Item number: TGM-T14913-100mg
Description: CD38 inhibitor 1 is an inhibitor of CD38. For hCD38 and mouse CD38, the IC50s are 7.3 nM and 1.9 nM. Target: CD38. Smiles: COCCO[C@H]1CC[C@@H](CC1)Nc1cc(=O)n(C)c2ccc(cc12)-c1cncs1. References: Haffner CD, et al. Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es as Potent CD38...
| Application: | CD38 inhibitor |
| CAS | 1700637-55-3 |
| MW: | 413.53 D |
From 51.00€
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CD38 Inhibitor 1
Item number: Cay35532-1
CD38 inhibitor I is an inhibitor of CD38 (IC50 = 17.7 nM). It is selective for CD38 over poly(ADP-ribose) polymerase 1 (PARP1), sirtuin 1 (SIRT1), and nicotinamide phosphoribosyltransferase (Nampt) when used at a concentration of 100 nM. CD38 inhibitor I (200 nM) increases NAD+ levels in mouse embryonic fibroblasts...
| Keywords: | CD38 Inhibitor 78c, CD38-IN-78c, 4-[[trans-4-(2-methoxyethoxy)cyclohexyl]amino]-1-methyl-6-(5-thiazolyl)-2(1H)-quinolinone |
| Application: | CD38 inhibitor |
| CAS | 1700637-55-3 |
| MW: | 413.5 D |
From 58.00€
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