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RS 17053 (hydrochloride)
RS 17053 (hydrochloride)

Item number: Cay33548-10

RS 17053 is an alpha1A-adrenergic receptor (alpha1A-AR) antagonist. It selectively binds to the alpha1A-AR (Ki = 2.5 nM) over alpha1B- and alpha1D-ARs (Kis = 50 and 79 nM, respectively). RS 17053 inhibits norepinephrine-induced contractions in isolated rat kidney and mesenteric arteries (pA2s = 9.8 and 9.9,...
Keywords: 5-chloro-N-[2-[2-(cyclopropylmethoxy)phenoxy]ethyl]-alpha,alpha-dimethyl-1H-indole-3-ethanamine, monohydrochloride
Application: alpha1A-adrenergic receptor antagonist
CAS 169505-93-5
MW: 449.4 D
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