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Item number: TGM-T7303-100mg

Description: Lixivaptan (VPA-985) is an orally active and selective vasopressin receptor V2 antagonist(Ki = 2.3 nM). Target: Vasopressin Receptor. Smiles: Cc1ccc(F)cc1C(=O)Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc23)c(Cl)c1. References: Wang X, Constans MM, Chebib FT.et al.Effect of a Vasopressin V2 Receptor Antagonist on...

Keywords:	WAY-VPA 985, VPA-985
Application:	Targets arginine vasopressin receptor 2 (AVPR2)
CAS	168079-32-1
MW:	473.93 D

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Lixivaptan

Item number: Cay21511-1

Lixivaptan is a nonpeptide antagonist of vasopressin V2 receptors (Ki = 2.3 nM). It is 100-fold selective for V2 over V1a. Formulations containing lixivaptan decrease urinary excretion of aquaporin-2 in patients with chronic heart failure and increase serum sodium levels in patients with hyponatremia due to...

Keywords:	VPA-985, WAY-VPA-985,...
Application:	Vasopressin V2 receptor antagonist
CAS	168079-32-1
MW:	473.9 D

From 44.00€ *

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