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PCC0208009
Item number: TGM-T4142-100mg
Description: PCC0208009 (IDO-IN-2) is an IDO inhibitor. Target: Indoleamine 2,3-Dioxygenase (IDO). Smiles: CC(C)CN(CC(C)C)c1ccc(cc1NC(=O)Nc1ccc(C)cc1)-c1ccccc1-c1nn[nH]n1. References: Jay A. Markwalder, et al. US20160200674A1. 2013.
| Keywords: | DO-IN-2, IDO inhibitor 1, IDO-IN-2 |
| Application: | IDO1 inhibitor |
| CAS | 1668565-74-9 |
| MW: | 497.63 D |
From 39.00€
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IDO-IN-2
Item number: Cay34876-1
IDO-IN-2 is an inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1, IC50 = 0.097 µM in HeLa cells). In vivo, IDO-IN-2 (100 mg/kg) decreases intratumor levels of Ki67, a marker of cell proliferation, and reduces tumor weight in a GL261 murine glioma heterotopic transplantation model. It also decreases mechanical and...
| Keywords: | PCC0208009, N-[4-[bis(2-methylpropyl)amino]-2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-3-yl]-N'-(4-methylphenyl)-urea |
| Application: | IDO1 inhibitor |
| CAS | 1668565-74-9 |
| MW: | 497.6 D |
From 43.00€
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