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Item number: TGM-T3230-100mg

Description: NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide), an intermediate capable of synthesizing glibenclamide, exerts an inhibitory effect on the formation of NLRP3 inflammatory vesicles in cardiomyocytes, limiting infarct size after myocardial ischemia/reperfusion in mice and has no effect on...

Keywords:	5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide, NLRP3 Inflammasome Inhibitor I
Application:	NLRP3 inflammasome inhibitor
CAS	16673-34-0
MW:	368.84 D

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NLRP3i

Item number: Cay30895-1

NLRP3i is an intermediate in the synthesis of glyburide (Cay-15009) and an inhibitor of the NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome. It is selective for NLRP3 over NLRP4 and absent in melanoma 2 (AIM2) inflammasomes at 400 µM. NLRPi inhibits LPS-induced IL-1beta release and...

Keywords:	N-[2-[4-(aminosulfonyl)phenyl]ethyl]-5-chloro-2-methoxy-benzamide
Application:	NLRP3 inflammasome inhibitor
CAS	16673-34-0
MW:	368.8 D

84.00€ *

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