Description: NOS-IN-1 (2-Imino-4-methylpiperidine acetate) is a potent and orally active inhibitor of NO synthase (NOS) isoforms. NOS-IN-1 exhibits IC50s of 0.1 µM, 0.2 µM, and 1.1µM for human iNOS (hiNOS), hnNOS and heNOS, respectively. Target: NOS. Smiles: CC(CCN1)CC1=N.CC(O)=O. References: R K Webber, et al....

2-Imino-4-methylpiperidine is a potent, general NOS inhibitor. It exhibits IC50 values of 0.1, 1.1, and 0.2 µM for inhibition of human iNOS, eNOS, and nNOS, respectively, at an arginine concentration of 30 µM.Formal Name: 3,4,5,6-tetrahydro-4-methyl-2-pyridinamine, acetate. CAS Number: 165383-72-2. Molecular...