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CGP60474
Item number: TGM-T14943-100mg
Description: CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC. CGP60474 is also a highly potent anti-endotoxemic agent and inhibits cyclin-dependent kinase (CDK) potently. Target: CDK, PKC, VEGFR. Smiles: OCCCNc1cc(ccn1)-c1ccnc(Nc2cccc(Cl)c2)n1. References: Kuo GH, et al....
| Application: | CDK inhibitor |
| CAS | 164658-13-3 |
| MW: | 355.82 D |
From 31.00€
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CGP 60474
Item number: Cay29631-1
CGP 60474 is an inhibitor of cyclin-dependent kinases (CDKs, IC50s = 0.017, 0.08, and 0.05 µM for Cdk1/cyclin B, Cdk2/cyclin A, and Cdk2/cyclin E, respectively). It is selective for these CDKs over Cdk4/cyclin D1 (IC50 = 0.7 µM) and a variety of other kinases, including several PKC isoforms (IC50s = 1.9->100 µM),...
| Keywords: | 3-[[4-[2-[(3-chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol |
| Application: | CDK inhibitor |
| CAS | 164658-13-3 |
| MW: | 355.8 D |
From 43.00€
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