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Item number: TGM-T11766L-100mg

Description: Eltanexor (ONO-7706) is an orally active exportin-1 (XPO1) inhibitor. It has effective anti-leukemic activity. Eltanexor inhibits XPO1-dependent nuclear export (EC50=60.9 nM) by directly targeting XPO1. Eltanexor causes caspase-dependent apoptosis in a panel of leukemic cell lines. Target: Others....

Keywords:	ATG-016, KPT-8602, ONO-7706
Application:	Targets exportin-1 (XPO1, CRM1)
CAS	1642300-52-4
MW:	428.29 D

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