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I-CBP112
Item number: TGM-T3969-100mg
Description: I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor targeting the CBP/p300 bromodomains. Target: Histone Acetyltransferase, Epigenetic Reader Domain. Smiles: CCC(=O)N1CCOc2c(C1)cc(cc2OC[C@H]1CCCN(C)C1)-c1ccc(OC)c(OC)c1. References: Zucconi BE, et al....
| Application: | P300 / CBP inhibitor |
| CAS | 1640282-31-0 |
| MW: | 468.59 D |
From 30.00€
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I-CBP112
Item number: Cay36811-1
I-CBP112 is an inhibitor of p300 and CREB-binding protein (CBP) histone acetyltransferases. It binds to the p300 and CBP bromodomains (Kds = 167 and 151 nM, respectively) and is selective for p300 and CBP over BRD4, as well as a panel of 104 nuclear receptors and ion channels and a panel of 32 enzymes at 10 µM....
| Keywords: | 1-[7-(3,4-dimethoxyphenyl)-2,3-dihydro-9-[[(3S)-1-methyl-3-piperidinyl] methoxy]-1,4-benzoxazepin-4(5H)-yl]-1-propanone |
| Application: | P300 / CBP inhibitor |
| CAS | 1640282-31-0 |
| MW: | 468.6 D |
From 88.00€
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