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AZD9496
AZD9496

Item number: TGM-T3975-100mg

Description: AZD9496 is an orally available selective estrogen receptor(ERalpha) antagonist, with potential antineoplastic activity. Target: Estrogen/progestogen Receptor, Estrogen Receptor/ERR. Smiles: C(C(C)(C)F)N1[C@@H](C2=C(C=3C(N2)=CC=CC3)C[C@H]1C)C4=C(F)C=C(/C=C/C(O)=O)C=C4F. References: Weir HM, et al....
Application: Estrogen receptor downregulator & antagonist
CAS 1639042-08-2
MW: 442.47 D
From 51.00€ *
Review
AZD 9496
AZD 9496

Item number: Cay21805-5

AZD 9496 is a potent and selective estrogen receptor downregulator (SERD) with an IC50 value of 0.138 nM for estrogen receptor alpha (ERalpha) downregulation. It is selective for ERalpha compared to other nuclear hormone receptors with IC50 values of 0.0008, 0.54, 9.2, and 30 µM for ERalpha, progesterone receptor...
Keywords: (2E)-3-[3,5-difluoro-4-[(1R,3R)-2-(2-fluoro-2-methylpropyl)-2,3,4,9-tetrahydro-3-methyl-1H-pyrido[3,4-b]indol-1-yl]phenyl]...
Application: Estrogen receptor downregulator & antagonist
CAS 1639042-08-2
MW: 442.5 D
From 60.00€ *
Review