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MAZ51
MAZ51

Item number: TGM-T8496-100mg

Description: MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor. Target: VEGFR, Apoptosis. Smiles: CN(C)c1ccc(\C=C2\C(=O)Nc3ccccc23)c2ccccc12. References: Kirkin V, et al. MAZ51, an indolinone that inhibits endothelial cell and tumor cell growth in vitro, suppresses tumor growth in vivo. Int J Cancer. 2004 Dec...
Application: VEGFR-3 VEGF-C antagonist
CAS 163655-37-6
MW: 314.38 D
From 34.00€ *
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MAZ51
MAZ51

Item number: Cay16168-1

The VEGF receptors (VEGFRs) mediate signaling leading to angiogenesis, with VEGFR3 (FLT4), activated by VEGF isoforms VEGFC and VEGFD, primarily expressed on lymphatic endothelial cells and directing lymphangiogenesis. MAZ51 is an indolinone that selectively antagonizes the activation of VEGFR3 by VEGFC (IC50 = 1...
Keywords: 3-[[4-(dimethylamino)-1-naphthalenyl]methylene]-1,3-dihydro-2H-indol-2-one
Application: VEGFR-3 VEGF-C antagonist
CAS 163655-37-6
MW: 314.4 D
From 66.00€ *
Review