3 products were found matching "163222-33-1"!
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Ezetimibe
Item number: TGM-T1593-100mg
Description: Ezetimibe (SCH 58235) is a dietary cholesterol absorption inhibitor that exerts its physiologic effect by decreasing cholesterol absorption. Target: NPC1L1, Autophagy, Nrf2, Others. Smiles: C(C[C@H](O)C1=CC=C(F)C=C1)[C@@H]2[C@H](N(C2=O)C3=CC=C(F)C=C3)C4=CC=C(O)C=C4. References: Clader JW, et al. J...
| Keywords: | SCH 58235 |
| Application: | Targets Niemann-Pick C1-like protein 1 (NPC1L1) |
| CAS | 163222-33-1 |
| MW: | 409.43 D |
From 42.00€
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Ezetimibe
Item number: Cay16331-25
Ezetimibe is an inhibitor of NPC1-like intracellular cholesterol transporter 1 (NPC1L1, Ki = 220 nM), a cholesterol transporter found in the apical membrane of enterocytes. It reduces cholesterol absorption in hamsters fed a high-cholesterol diet (ED50 = 0.04 mg/kg per day). Ezetimibe (346 nM) also reduces the...
| Keywords: | Ezetrol, SCH 58235, (3R,4S)-1,4-fluorophenyl-3-[(3S-3-4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone |
| Application: | NPC1L1 inhibitor, intestinal cholesterol absorption inhibitor |
| CAS | 163222-33-1 |
| MW: | 409.4 D |
From 100.00€
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