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Item number: Cay22460-1

BAR501 is a selective agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1, EC50 = 1 µM) that lacks activity at the farnesoid X receptor (FXR). In vivo, BAR501 reduces hepatic perfusion pressure and counteracts norepinephrine-induced vasoconstriction in naïve rats. It protects against development...

Keywords:	(3alpha,5beta,6beta,7beta)-6-ethyl-cholane-3,7,24-triol
Application:	Selective GPBAR1 agonist
CAS	1632118-69-4
MW:	406.6 D

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