2 products were found matching "1632006-28-0"!

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Item number: Cay41082-10

Esaxerenone is a non-steroidal mineralocorticoid receptor antagonist (IC50 = 9.4 nM). It is selective for mineralocorticoid receptors over glucocorticoid, androgen, and progesterone receptors (IC50s = >10,000 nM for all). Esaxerenone (0.3, 1, or 3 mg/kg) increases the urinary ratio of sodium to potassium in...

Keywords:	CS-3150, 1-(2-hydroxyethyl)-4-methyl-N-[4-(methylsulfonyl)phenyl]-5S-[2-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide
Application:	Non-steroidal mineralocorticoid receptor antagonist
CAS	1632006-28-0
MW:	466.5 D

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Esaxerenone

Item number: TGM-T15246-100mg

Description: Esaxerenone (XL-550) is a highly potent and selective non-steroidal antagonist of the mineralocorticoid receptor. Target: Glucocorticoid Receptor. Smiles: Cc1c(cn(CCO)c1-c1ccccc1C(F)(F)F)C(=O)Nc1ccc(cc1)S(C)(=O)=O. References: Yamada M, et al. Pharmacokinetics, distribution, and disposition of...

Keywords:	CS-3150, XL-550
Application:	Targets mineralocorticoid receptor (NR3C2, MR)
CAS	1632006-28-0
MW:	466.47 D

From 63.00€ *

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