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Item number: TGM-T29135-100mg

Description: VU0422288 (ML396) is a potent orthosteric modulator of type III mGlu receptors (mGlus).VU0422288 shows inhibition of mGluR4, mGluR7, and mGluR8 in a calcium mobilization assay.VU0422288 can be used to study Rett syndrome (RTT). Target: GluR. Smiles: Clc1ccc(Oc2ccc(NC(=O)c3ccccn3)cc2Cl)nc1. References:...

Keywords:	ML 396, VU 0422288, VU-0422288, ML-396, ML396
Application:	Group III metabotropic glutamate receptor positive allosteric modulator
CAS	1630936-95-6
MW:	360.19 D

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ML-396

Item number: Cay29167-1

ML-396 is a positive allosteric modulator of group III metabotropic glutamate receptors (mGluRs) with EC50 values of 108, 146, and 128 nM for mGluR4, mGluR7, and mGluR8, respectively, in calcium mobilization assays. ML-396 potentiates LSP4-2022-induced reductions in paired-pulse field excitatory post synaptic...

Keywords:	VU0422288, N-[3-chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]-2-pyridinecarboxamide
Application:	Group III metabotropic glutamate receptor positive allosteric modulator
CAS	1630936-95-6
MW:	360.2 D

From 44.00€ *

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