2 products were found matching "162401-32-3"!

No results were found for the filter!
Roflumilast
Roflumilast

Item number: TGM-T1024-100mg

Description: Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potential antineoplastic activities. Upon administration, roflumilast and its active metabolite roflumilast N-oxide selectively and competitively bind to and inhibit...
Keywords: BYK 20869, B9302-107, APTA 2217, BY 217
CAS 162401-32-3
MW: 403.21 D
From 52.00€ *
Review
Roflumilast
Roflumilast

Item number: Cay15141-25

Roflumilast is an inhibitor of phosphodiesterase 4 (PDE4, IC50 = 0.8 nM). It is selective for PDE4 over PDE1, -2, -3, and -5 (IC50s = >10, >10, >10, and 8 µM, respectively). Roflumilast inhibits the production of leukotriene B4 (LTB4, Cay-20110) induced by fMLP (Cay-21495) in isolated human neutrophils with an IC50...
Keywords: B 9302-107, BY 217, BYK 20869, 3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)-benzamide
Application: PDE4 inhibitor
CAS 162401-32-3
MW: 403.2 D
From 33.00€ *
Review